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Wim Hof Method & The Nobel Prize in Physiology or Medicine

February 12, 2020

This year’s Nobel prize in physiology or medicine was awarded to three researchers. William Kaelin, Peter Ratcliffe and Gregg Semenza These researchers helped reveal the mechanism by which cells in the body sense and adapt to low oxygen availability. Mechanisms that has deepened our understanding and ability to treat disease such as anaemia and cancer. When the body is experiencing low oxygen levels, A protein complex builds up in nearly all the cells in the body. This protein complex is called HIF or hypoxia induced factor. HIF has a number of effects on the body. Including the formation of new blood vessels and strikingly seems to up-regulate the expression of a gene used to produce erythropoietin (EPO). A hormone that stimulates the creation of new (oxygen carrying) red blood cells. Why is this so important to the method? Because the Wim Hof breathing method simulates this low oxygen stress throughout the body. Through deep controlled breathing, blood is alkalised. This alkaline blood effects the release of oxygen in the body and allows a person to hold their breath for a long time. Meaning oxygen saturation in the body can lower to unprecedented levels. This was shown in the Radboud study. Where Wim managed to lower his blood oxygen saturation to levels that would literally turn off the oximeter measuring him. The participants of the Radboud study also demonstrated this low oxygen saturation. Have a look. Lowering deeper and deeper after each round! This low oxygen stress on the body could stimulate greater expression of the HIF protein. Allowing a person to reap the benefits this protein offers at home, through natural means. This research can also help explain how Wim Hof could train himself and others to adapt to high altitudes quickly with his breathing technique. Climbing Everest or Kilimanjaro. In shorts no less! In this spirit, we would like to thank these researchers. For many years Wim has been trying to get the message out there and there seems to only be more evidence everyday. Humbly. We thank you.


  • Reply Luca Bertani November 2, 2019 at 4:38 pm

    Wim Hof learned from ancient wisdom passed down through the generations, remember that. He is also a true original, don't forget. Such is life.

  • Reply Urigehead Mot November 2, 2019 at 4:44 pm

    Wim Hof we love you in Austria!

  • Reply 92laird November 2, 2019 at 8:47 pm

    Don't eat shit food and get off the couch and won't have to worry about many health issues

  • Reply Issack Vaid November 2, 2019 at 10:41 pm

    Everyone should know about this! All thanks to those Nobel Prize winners and an even greater thanks to Wim Hof! If you suffer from migraines like me, I can assure you this method of breathing is the way to go!

  • Reply Nick Robertson November 2, 2019 at 11:36 pm

    Amazing. The science has finally caught up with the practice. Good news for us distance runners too, with the greater EPO production. Right on.

  • Reply TOUATI Yousseuf Abd Elhadi November 2, 2019 at 11:40 pm

    Wim Hof vs Pharmaceutical industries …

  • Reply Don Antonio November 3, 2019 at 1:27 am

    So awesome

  • Reply Don Antonio November 3, 2019 at 1:28 am


  • Reply Mr Matt November 3, 2019 at 3:06 am

    Lol this isn't anything new, ask anyone in deep meditation as it slows your breathing, also why people do buteyko

  • Reply Someone November 3, 2019 at 3:20 am

    We love you,Wim!

  • Reply Fox Dylan November 3, 2019 at 3:28 am

    Is this similar to what free divers do?

  • Reply Roberto Juarez November 3, 2019 at 3:44 am

    Mo entiendo nada. Pongan esto aunque sea con somubtitulos en espaรฑol.

  • Reply ะ’ะธะบั‚ะพั€ ะžัั‚ะฐะฟะตะฝะบะพ November 3, 2019 at 6:51 am

    hi! cant connect this news with WHM. can somebody explain physiological mechanism?when u breathing u becoming alcaline cause u are getting A LOT OF O2 inside a lot of. so where is the hypoxie?

  • Reply Dmitrii Zholud November 3, 2019 at 8:28 am

    As a freediver in the past I can surely say things are much more complex with hyperventilation. It is flushing CO2 that allows you to โ€œnot want to breathโ€ and it is very dangerous (freedivers donโ€™t do hyperventilation) because O2 goes down indeed without you noticing it and blackout comes unexpectedly. It does not prolong your breath hold. It only shuts down the urge to breath for a while (if you have low willpower and give up quickly – you will be able to hold breath longer, but thatโ€™s far from your maximum breath hold). And I am pretty sure the mechanism that Nobel prize winners describe can not be triggered by hyperventilation. So no, this does not confirm Wim Hof.

  • Reply Bryce Bro November 3, 2019 at 1:45 pm

    Iโ€™m so confused everyday on the internet cause yesterday I was just reading about Hyperbaric chambers and how slaming oxygen into ur cells is good…. now people are winning Nobel prizes for the opposite…

  • Reply Google User November 3, 2019 at 2:38 pm

    The therapeutic effects of hypoxia is well known for thousands of years… So, be more modest.

  • Reply FAIL FORWARD FAST November 3, 2019 at 3:33 pm

    Won hof is a nerd.

  • Reply vcasted November 3, 2019 at 4:10 pm

    Unfortunately this is still all hypothesis. But I do enjoy me some breathing in and letting go regardless.

  • Reply putin Vladimir November 3, 2019 at 7:48 pm

    It has been proven that, in relation to normal tissues, HIF is activated in solid tumors. This behavior generally results from a combination of local hypoxia and an increased level of HIF activation of cancer cells for a given oxygen pressure. In most studies, although not all, the tumors for which HIF activation is more marked, are associated with greater clinical severity. In some experimental studies in which a group of cells are implanted in immunodeficient mice, HIF inactivation has potent effects that generally lead to a reduction in angiogenesis and tumor growth. However, several studies have revealed that the growth of HIF-deficient tumors is in fact faster, which is not entirely surprising given the pleiotropy of the annexed effects of HIF.

  • Reply Hรฉlรจne Drouin November 3, 2019 at 8:55 pm

    It all looks great, except for cancer patients or those who want to prevent it. As this breathing cycle stimulates the fabrication of new blood vessels (angiogenesis) via IGF (Ipoxia induced factor), doesn't it contribute to the development of tumors? In cancer, stimulating angiogenesis means promoting tumor growth and metastasis! Did these researchers address this issue?

  • Reply B. Mill November 4, 2019 at 2:22 am

    Wim will this help during benzo withdrawls? Iโ€™m already feeling some benefits but I want to know your opinion. Much love!

  • Reply The only Crazy World November 4, 2019 at 2:26 am

    Indian sages have been preaching hundreds of breathing methods like this for thousands of years called โ€˜pranayamโ€™ .Sad that the world has forgotten about them.This is just a modification of what has been already existing since hundreds of years in Hinduism and Buddhism

  • Reply Hairy Kerry November 4, 2019 at 2:55 am

    Congratulations Wim! That's as much your prize as anyone who measured your achievements. You were the one who actually lead scientists to a Nobel prize. Amazing.

  • Reply Jolanda Meivogel November 4, 2019 at 6:59 am

    Goed gedaan Wim!!!! Je zoon heeft mij in 2016 enorm geholpen toen Ik in het ziekenhuis lag.

  • Reply upsidedahead November 4, 2019 at 8:57 am

    If I type Wim Hof my autocorrect wants to write….

    Win God

  • Reply ThomasVermaelen01 November 4, 2019 at 10:19 am

    i thought the point of wim hof method was to saturate blood with oxygen not depleat it?

  • Reply Remon November 4, 2019 at 1:15 pm

    @Wim Hof, are you familiar with the "Buteyko Method" ? it would be interesting to see a discussion/collaboration effort between the buteyko method and wim's own insights. They differ but also have lots of overlapping !

  • Reply BearDog November 4, 2019 at 2:42 pm

    HIFs aren't complexes. They are individual proteins. It's also not at all surprising that hypoxia induces EPO expression.

    Anyhow, this prize is not about Wim's method. It's not at all as if the aim of these researchers was to find a way to support Wim's method.

    Seriously. How stupid do you think we are?!

  • Reply rga Swaei November 4, 2019 at 5:54 pm

    Who esle is a true fan of WIM HOFF ๐Ÿ‘‡
    (gifting next 48 subscribers)

  • Reply equisdemaniaco November 4, 2019 at 7:14 pm

    There are 0 references to scientific papers. How do you expect that people with certain scepticism will believe you?

  • Reply Mora Young November 4, 2019 at 8:13 pm

    Wonderful that explains some of the si thorns we people from high altitude have bigger lungs to stored more oxygen for the brain to function.

  • Reply Sean Mitchell November 4, 2019 at 9:35 pm

    Hello so I've been studying the wim hof method for sometime. I've only done this method twice out of skepticism and I honestly seen a difference in my mood and my energy level within the first 3 days. My question is does it matter how long you hold your breath? I can not hold my breath for 2 min. But I also suffer from fear of suffocation or drowning. So if I produce more adrenaline in doing this even tho I do not hold for 2 min. Is this still effective?

  • Reply Julia K November 4, 2019 at 10:43 pm

    Wearing Occlusion Bands around arms and tights during the exercises brings perfect hypoxia. Even elder people can do this and get rid of many diseases.

  • Reply Miguel Ibarra November 5, 2019 at 12:10 am

    Humbly thank you

  • Reply Mark D November 5, 2019 at 2:19 am

    Im pretty sure he learned it from the munks

  • Reply Ankur Tiwari November 5, 2019 at 3:16 am

    This is what Tebitan Monks and Hindu saints did for thousands of years. Yoga with breathe control on high altitude.

  • Reply Johny Doe November 5, 2019 at 3:27 am

    Wim Hof should get the Nobel Prize………?

  • Reply Volvox November 5, 2019 at 7:12 am

    I don't understand… isn't the breathing for "oxygenizing the body and all the cells" as Wim says it in his videos not for LOWERING the oxygen level?

  • Reply Aravind Kannoly November 5, 2019 at 8:53 am

    Wasn't there some talk about Greta getting the Nobel? ๐Ÿ˜‚

  • Reply BsBigSpinToTheShin November 5, 2019 at 2:40 pm

    This is amazing, was wondering what the significance of the breath retention was for. Have had some intense sensations in that state

  • Reply Fotis K November 5, 2019 at 6:11 pm

    Should we practice the Wim Hof Method everyday ? Breathing and then cold shower? Or 2-3 times a week is OK?Is it OK if we do the breathing in the morning and the cold shower in the evening?

  • Reply Patti S. November 5, 2019 at 6:51 pm

    Breathing and cold showers helped me within a week to loose my body pain. I am very thankful!

  • Reply Working Title November 5, 2019 at 10:05 pm


  • Reply apyt100 November 5, 2019 at 10:37 pm

    I thought the wim method increased oxygen not lower it?

  • Reply Sandy Lengerich November 5, 2019 at 10:39 pm

    I love Wim Hof

  • Reply zemba val November 6, 2019 at 12:45 am

    There is still no evidence that wim hof method induces endogene EPO synthesis.

  • Reply Monsi November 6, 2019 at 4:09 am

    When doing the method, I get the same feeling as when I smoke a cigarette, is it the same effect?

  • Reply jean-marc lamothe November 6, 2019 at 4:37 am

    I'm in my 11th months of using the method and so far it looks like it's working (I'm 56 years old). I've been sick one time in febuary with small fever but I have recover faster than never! after four days I was back in the gym to workout with cardio! I used to be sick for several days for many years before, because any cold could be transformed in bronchitis easily and I had to use ventolin pump etc. I had some days in the years feeling not in good shape but once again the recovery was fast! My record is four and a half minutes without breath! The cold shower took me months to achieve the two minutes but now I seem used to it. I went outside ( leaving in Quebec, canada) two weeks ago at 3.5 degree Celsius and did my cold bath in the pool at 11 degree Celsius for two minutes. So slowly i am progressing. It takes a lot of perseverance and discipline to do my five breathing every morning when I wake up and then the cold shower for two minutes but it worth it.
    I wish I could meet Win one day and may be trained with him at his place.

  • Reply Ariel O November 6, 2019 at 6:57 am

    Link to the official Nobel prize website:

  • Reply FreeGoro November 6, 2019 at 10:22 am

    Day 50 of Wim Hof: I can now taste colours, hear smells and can levitate for short bursts.

  • Reply luckyluis November 6, 2019 at 10:36 am

    Thank you Wim Hof. God bless you.

  • Reply J C November 6, 2019 at 10:56 am

    Anyone please correct me, but isnโ€™t he doing pranayama exercises? Those have been around for thousands of years.

  • Reply Mike Hackenschmidt November 6, 2019 at 3:39 pm

    Wim Hof or Wom Hif?

  • Reply Mike Kortram November 6, 2019 at 4:16 pm

    Pranayama ?

  • Reply Jaq Chib November 6, 2019 at 6:42 pm

    Well, HIF expression is associated with angiogenesis witch is a factor of bad prognosis in the case of cancer developpment. I'd like to read the scientific article to understand how the WH technic is still good for people with cancer as it is mentionned.

  • Reply Mix Kurmil November 6, 2019 at 8:19 pm

    ะ ะณะดะต ะฝะฐ ั€ัƒััะบะธะน ะฟะตั€ะตะฒะพะด, ะฝะฐั… ะผะฝะต ั‚ะฐะบะฐั ั€ะฐััั‹ะปะบะฐ?

  • Reply Amit k. Das November 6, 2019 at 8:27 pm

    Thank you too, Wim… the great master.๐Ÿ™๐Ÿฝ๐Ÿ™๐Ÿฝ๐Ÿ™๐Ÿฝ

  • Reply keeponpainting November 6, 2019 at 9:40 pm

    They should name it the HIF-HOF protein ๐Ÿ™‚

  • Reply Gabe Kaviani November 7, 2019 at 6:09 am

    Yo, my hands locked up for like 5 minutes after I did the breathing technique today. Should I be concerned at all?

  • Reply Hakuraita November 7, 2019 at 7:48 am

    Can I use this to slay demons?

  • Reply Rokas Peleckas November 7, 2019 at 2:05 pm

    I tried it yesterday initially could hold my breath for 1min, after half an hour of Wim Hof breathing I went up to 2m 30sec. WTF? That's the longest I have ever held my breath ever.

  • Reply christopher lobato November 7, 2019 at 9:09 pm


  • Reply Matias November 8, 2019 at 1:20 am

    How someone could ever dislike this guy is beyond me.

  • Reply ะะปะตะบัะฐะฝะดั€ ะ›ะฐั€ัะตะฝ November 8, 2019 at 8:40 pm

    Hello from Murmansk, Russia, Wim! We have lots of cold ! Haha
    I have a question for you. I would like to get a little bit taller then I am right now. May I do this with your breath technique? If yes, what am I supposed to do?

  • Reply Nugget the great November 8, 2019 at 10:07 pm

    Man since i watched one of his vid( a year and a half ago) i started resisting and appresiating xold now i can get a bath of cold water and i never get sick:)

  • Reply Khadijah Joy Sams November 9, 2019 at 3:09 am


  • Reply mono November 9, 2019 at 9:14 am

    The method really works i'm practicing it every morning for almost a year now but the way the information in this video is presented is a bit disingenuos like the short note in the corner that this is a hypothesis and the way the graph actually goes from 40-100% to make the difference seem more dramatic than it actually is. The method is impressive by itself no need to dilute it with cheap marketing tactics and double speak.

  • Reply Zetsuke4 November 11, 2019 at 1:30 pm

    Brilliant! Well deserved prize.

  • Reply Zetsuke4 November 11, 2019 at 1:32 pm

    What is the win hof method? Short in 31 words or less

  • Reply Lady August November 11, 2019 at 7:10 pm

    Just got started with snow bath and breathing technique and it is amazing! Feels so much better, thank you very much!

  • Reply Dmitriy Rybkin November 11, 2019 at 8:37 pm

    Buteyko method?

  • Reply kevin mntambo November 12, 2019 at 2:44 pm

    Win deserves a price as well๐Ÿ˜ข

  • Reply n morovati November 12, 2019 at 8:43 pm

    Hi dear Wim, when I do this I feel cold.Is it natural? Anyway I feel great aftrrwards, so thank you ๐ŸŒท๐ŸŒท

  • Reply Al Muaafa Maher November 13, 2019 at 12:46 pm

    Win Hof doesnโ€™t need the Noble prize. The Noble Prize needs him!

  • Reply Random November 13, 2019 at 9:05 pm

    4 months here, finally I don't need my coat, thank you Wim :)))

  • Reply Anastacia November 14, 2019 at 1:32 am

    Perhaps this means people who get leukemia are simply not breathing deeply enough.

  • Reply Sosa November 14, 2019 at 5:52 am

    Do you sleep with a blanket Wim?

  • Reply Gops bull November 14, 2019 at 9:20 pm

    Hallo, look at this inspiring video:

  • Reply Sameer Hinduja November 15, 2019 at 7:10 am

    Cannot think this man enough. ๐Ÿ™๐Ÿฝ๐Ÿ™๐Ÿฝ๐Ÿ™๐Ÿฝ๐Ÿ™๐Ÿฝ I love you man. You are blessed for this.

  • Reply Welby Northmore MW November 18, 2019 at 11:37 pm

    Not great for cancer patients practicing the methods though unless I misunderstood something?!? Hypoxia encourages cancer spread doesnt it?

  • Reply easybullet3 November 22, 2019 at 5:37 pm

    climbing high altitute mountain in shorts !! Thats awesome ๐Ÿ™‚

  • Reply tarik bajric November 22, 2019 at 6:42 pm

    As someone who studies medicine listening to wim genuinly makes my day. Wim, mate, you're full of shit mate.

  • Reply tarik bajric November 22, 2019 at 6:44 pm

    Sack full of shit.

  • Reply Choppi balboa November 22, 2019 at 8:46 pm

    Hmm, I thought that by the method you increased the level of oxygen in the body…

  • Reply Agnieszka Wierzbicka November 23, 2019 at 6:25 pm

    Love Wim Hof ๐Ÿ’™๐Ÿ’š๐Ÿ’›๐Ÿ’œ๐Ÿ’œ๐Ÿ’›๐Ÿ’š๐Ÿ’™๐Ÿ’™๐Ÿ’š๐Ÿ’›๐Ÿ’œ๐Ÿ’™๐Ÿ’š๐Ÿ’›๐Ÿ’œ๐Ÿ’›๐Ÿ’š๐Ÿ’™๐Ÿ’š๐Ÿ’›๐Ÿ’š๐Ÿ’›๐Ÿ’œ๐Ÿ’™๐Ÿ’™๐Ÿ’™๐Ÿ’™๐Ÿ’š๐Ÿ’š๐Ÿ’š๐Ÿ’›๐Ÿ’›๐Ÿ’›๐Ÿ’œ๐Ÿ’œ๐Ÿ’œ๐Ÿ’›๐Ÿ’š๐Ÿ’™๐Ÿ’š๐Ÿ’›๐Ÿ’œ

  • Reply Hendrik Aufderheide November 23, 2019 at 7:51 pm

    Congratulations for the Nobel price. Thank you for your work and the change it does to me and us as humanity

  • Reply Danny Mesaros November 23, 2019 at 11:02 pm

    In combination with weed is it even better!

  • Reply Fluxsiarski November 24, 2019 at 5:49 pm

    inhalations are to be quick during methods or slow because everywhere writes differently

  • Reply J BELL November 26, 2019 at 3:47 pm

    merci { thank you }

  • Reply Natural Chef Shobhan November 27, 2019 at 10:10 am

    Thank you

  • Reply November 27, 2019 at 10:35 pm

    Finally understood what this breathing 30 times and holding 1 min. method was supposed to create in the body. It works !

  • Reply 19grand November 30, 2019 at 7:19 pm

    Thank you Wim. Thank you for sharing your knowledge. Thank you for your compassion. Thank you for considering those who suffer. Thank you and those around you for you.

  • Reply augenmaugen December 5, 2019 at 2:31 pm

    Why didnโ€™t Wim get a Nobel prize?

  • Reply JERIN ANTONY December 18, 2019 at 10:17 am

    What I think is that wim has been gifted some special ability to do all this crazy's mostly genetics at play

  • Reply Max Hodges January 2, 2020 at 1:52 pm

    Us freedivers have been doing apena training for decades. We do high Co2 and low O2 tolerance training because of these benefits. We've known about the benefits for decades, it's just taking scientists this long to figure out the mechanism.

  • Reply Typos TranscEND January 15, 2020 at 10:59 pm

    Low oxygen ? I thaught the aim was to increase it

  • Reply Turtle Person January 23, 2020 at 7:32 am

    Just realized my boi is doing Total Concentration Breathing

  • Reply Rien q'un sac ร  dos January 27, 2020 at 3:46 am

    Blablabla ! I did the Technique for 1 year and it did nothing for me.
    So many people are looking for a messiah.

  • Reply Donovan Collier January 28, 2020 at 6:13 pm

    Im curious how wim figured this all out anybody know how he discovered all this?

  • Reply Fleisch Berg February 1, 2020 at 11:19 pm

    This is so good. God bless Wim Hof & all beings ๐Ÿ™‚

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