Articles, Blog

The Beast in Yeast: OPATHY

August 17, 2019

May I introduce you to the world of yeasts. Our everydays little helpers. They make our bread, our wine and beer. You can find them almost everywhere,
even on our skin, where they build colonies. Most strains of yeast are completely harmless
but there is some out there, that share a dark secret. This Lady for example,
is an offspring from the renown yeast-family named Candida. A nice little cell – but from time to time,
especially when our immune defense is weak, miss candy shows her darkest secrets,
inflamating some of peoples most delicate spots. Yeast infections like to strike,
when immune defense is weak. And if they do,
they are often confused with bacterial infections up until it is too late. It’s really hard to spot the beast in yeast! Let me show you something. Pathogenic Bacteria. Our everyday business. We can kill most of them, using antibiotics. And now look at this – a yeast colony… Like the friendly neighbour next door. If yeast goes berserk,
it looks like a bacterial infection so we give our patients antibiotics
where we should use funghicides. A deadly mistake
as Antibiotics do not affect the yeast at all. Even worse, they pave the way for it to grow,
where harmless bacteria once settled. This is why, pathogenic yeast is often discovered
late, and if it manages to enter our bloodstream
sometimes too late. Pathogenic Yeast – this means – 300 Million
Infections Worldwide – but science has an answer: OPATHY! All over Europe,
the OPATHIANS are out, a group of fearless scientists,
confronting and collecting yeast, wherever it causes troubles. Once we spot a pathogenic yeast,
we send a sample to the OMICS Organisation, a kind of scientific intelligence service… Welcome at the Omics Organisation. The OMICs are experts in their field. Once a strain is in their hands,
their interrogation experts squeeze every possible piece of information out of
it. I read the genes and try to understand the
code. I am interested in the way, the code is translated
into real life. I am interested in proteins and what they
do. We are the OMICS,
we analyse, we understand and recommend. And this is the great digitator,
our beloved Supercomputer that stores and processes
all the molecular data we receive. The vast number of data in combination
with the analytic superpower provided by state of the art computing,
makes it possible to spot specific patterns in the behaviour of pathogenic yeast
and therefore detect those strains, that may cause trouble one day. A first step towards
an early detection and warning system, that will help medics around the world,
to chose the rigth treatment. Observed like never before yeast
will face a peaceful symbiotic future on our bodies or else have to face a harsh treatment.

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