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Streptococcus pyogenes quick review

October 16, 2019


Streptococcus pyogenes is a gram positive
cocci that causes group A streptococcal infections. Strep pyogenes typically produces large zones
of beta-hemolysis and can be distinguished from other streptococcal organisms because
it is catalase negative and bacitracin sensitive. It can cause a variety of disease including
pyogenic infections of the pharynx and skin. In the pharynx, it is the classic cause of
bacterial strep throat. In the skin, it can cause impetigo and cellulitis. This bacteria
also causes several diseases mediated by toxins including scarlet fever and toxic shock like
syndrome. Two of the major complications of group A strep infections are mediated immunologic
mechanisms, including rheumatic fever caused by the development of antibodies to M protein
and acute glomerulonephritis.

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