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Coronavirus Epidemic Update 29: Testing problems, mutations, COVID-19 in Washington & Iran

March 3, 2020


welcome to another MedCram COVID-19
update and I have been off for a few days from the updating because it was my
turn to take the helm of the ICU what we’re gonna be talking about is number
one five new deaths in Washington State yesterday we are definitely in the
growth phase here in the United States but we can’t tell how much of a growth
phase there is because we’re gonna talk about testing and the lack of testing
and we’re also going to talk about preparation what to do before this hits
now we’ll talk about mutations we are at a total confirmed worldwide cases here
upwards of 90,000 total deaths is over 3,000 total recovered is well over 10
times that at 47,000 and those are the published numbers I’ve heard a number of
people talk about the numbers in Asia and the model to look at in some
people’s opinion is going to be South Korea because it is a country that’s
doing very aggressive testing and it’s an open and democratic country but I
think the biggest thing there is the fact that they are aggressively testing
and that’s not something that we’re doing yet here in the United States for
a number of reasons which we’ll talk about going over to the world ometer
website we look at the close cases to kind of get an idea of where we’re going
on the mortality because these are close cases you’ve either recovered or you
haven’t and if you look at this graph you can see that the mortality rate
continues to drop these are people that were tested and we’re already at about
6% that’s good to go much lower than that once we get the full scope of the
infection here we have total cases worldwide things were starting to level
off here and I think the reason why we’re starting to accelerate again is
because we’re going into the epidemic phase in a number of these other
countries and looking at latest updates for today March 3rd maybe a little bit
behind because this is a fluid situation by the time this gets published
there are 477 new cases and six deaths already today in South Korea of course
South Korea being in the part of the world that is the farthest ahead in time if we look at yesterday we have the
first case in Morocco this was somebody from Italy yesterday 21 new cases and
five new deaths here in the United States and looking to Washington’s going
to be very important to see what’s going to work in this country and what’s not
going to work notice that a lot of these people who
are dying are in their 70s however there is a man in his 40s hospitalized in
critical condition in Kirkland one in Rhode Island and that was a teenager
contact of the previous case and all of these people again went to the same trip
to Italy they’re saying here this is precisely why we are being so aggressive
in identifying contacts and testing people who are symptomatic there are
three people in California and Santa Clara County including a couple whose
recently traveled to Egypt and there are now two in Oregon one an adult in a
County Hospital in Walla Walla Washington and the other is a contact of
the first case in Oregon who is recovering at home there’s two new cases
in Florida and that is the first one in New York interesting interview on CNBC
that’s also here on the ward ometer website dr. Mack McCarthy who is a ER
physician at New York Presbyterian he says I’m here to tell you right now at
one of the busiest hospitals in the country I don’t have at my fingertips a
rapid diagnostic test I still have to make my case plead to test people this
is not good we know that there are 88 cases the United States they’re going to
be hundreds by the middle of the week they’re going to be thousands by next
week and this is a testing issue quote in New York State the person who tested
positive is only the 32nd test we’ve done in this state that is a national
scandal they’re testing 10,000 a day in some
countries and we can’t get this off the ground McCarthy said I’m a practitioner
on the firing line and I don’t have the tools to properly care for patients
today and I can tell you I resonate with that as a health care work I was in the
ICU all last week seeing patients in the emergency room we are taking protective
measures to make sure that we don’t get exposed to people coming in to the
hospital with kovat 19 causing a lot of our health care workers to be
quarantined and so it’s really important that if anybody goes to the emergency
room to call ahead make sure that they’re following instructions make sure
that they’re wearing a mask especially if they have a fever and they have
symptoms because anybody that they in fact no matter who they are will have to
be quarantined and of course if those people that are being quarantined are
health care providers well that’s just less people to be able to care for other
people that need it now the good news there is that as I understand it there
are going to be a lot more tests available but they’re not going to be
available until later this week there are regulations that the FDA imposes on
commercial manufacturers of these tests they have to reach certain goals and
it’s a long and laborious procedure to get these things approved by the FDA
those are being relaxed so we can get enough tests on a market and get labs up
and running what you ideally want to do and this goes back to the days of
medical school when he were trained in surgery it was always a good thing if
you took somebody occasionally to surgery for appendicitis and you pulled
out a completely normal appendix that means that you were not missing any that
means you work finding negative test results true negatives so you actually
need to screen widely enough so that you know you’re getting enough negative
testing what you don’t want to be doing is testing so limited that the number of
tests that you’re getting you’re not catching the full magnitude of the
infection and so I think everyone believes and everyone’s on the same page
here that the amount of testing that needs to be done right now in this
country needs to be ratcheted up by orders of magnitude over what we’re
getting right now here’s a story that was published in the AP couple of days
ago and it talks about what’s going on especially up in Washington where the
hot spots are says here as Americans prepared researchers at the Fred
Hutchinson Cancer Research Center and the University of Washington on Sunday
said that they had evidence the virus may have been circulating in the state
for up to six weeks undetected a finding that if true could mean hundreds of
undiagnosed cases in the area they posted their research online but it was
not published in a scientific journal or reviewed by other scientists trevor
bedford and associate professor who announced the
findings on the virus in Washington State said on Twitter late Saturday that
genetic similarities between the states first case On January 20th and a case
announced Friday indicated at the newer case may have descended from the earlier
one now this is gonna be something that we’re going to talk about when we talk
about molecular biology is this idea about descendants so the thing that
you’ve got to understand is that the virus when it infects your cell it takes
over the cells machinery to create more viruses but the genes that the virus
brings in the kind of sloppy and so because of that sloppiness there’s a lot
of mutations that are made and some of those mutations may actually end up
changing amino acids some of those mutations won’t translate into
difference in amino acids but you can still see those mutations and as you
track those mutations in time you can see which virus strain descended from
another now those mutations can occur randomly anywhere along the genetic
thread the RNA as it turns out in this case with corona virus but if those
mutations affect a key component for instance the binding protein or the
spike protein on the corona virus that allows it to infect human cells
well that virus is just not going to be able to infect the next human cell but
because there’s millions and millions that are made there’s always another one
right behind it that’s going to happen the bottom line is you rarely are going
to see viruses copies of the virus infecting human cells that have a
mutation that is critical in the binding of that protein and therefore the
binding of that site now in this case the binding site in the human being is
the ACE 2 receptor in the cells in the bronchi or the lining of the lungs so
that’s a highly conserved area why is that it’s highly conserved because those
are the only viruses that are going to infect the human being but if you look
at these just like the human race has different families different last names
because they’re related to each other different coronaviruses different SARS
come to different kovat 19 viruses in other words if you were to look at the
ones in wuhan versus the ones in Washington they are not identical to
each other they have mutated in some way and what you can do is actually come up
with family tree and you can see where these
things came from they say I believe we’re facing an already substantial
outbreak in Washington State that was not detected until now due to narrow
case definition requiring direct travel to China scientists not affiliated with
the research said the results did not necessarily surprise them and pointed
out that for many people especially the younger healthier ones the symptoms are
not much worse than the flu or a bad colds he says we think that this has
been a pretty high rate of mild symptoms and can be asymptomatic the symptoms are
pretty nonspecific and testing criteria that has been pretty strict and this is
really the key here up to this point you could not get testing unless you had
traveled to that specific portion of China where the virus was so these
combinations of factors means that it easily could have been circulating for a
bit without knowing suggestin less ler so people are saying that this is high
quality work so what I want to do is talk a little bit more about what is
going on with this mutation and I want to introduce you to a really cool site
and that website is called neck strain and this actually does real-time
tracking of pathogen evolution if we click on the latest data and analysis
here what we’ve got here is the SARS cuff to genome and I think this is
really cool what you can see here we have the initial strain over here and we
can see how through time the DIF mutations have occurred in a different
family trees so if we play this you can see that things started out here in
Wuhan but as things have spread across the world there’s been mutations and we
can see what the descendants are as we track it so interestingly the one here
in California it shows that there are nucleotide mutations from the original
there are amino acid mutations in the ORF 1a gene we’ll talk more about that
that is the gene in the virus that codes for the protein that allows it to
reproduce the RNA genome of the virus and if we look down here we can actually
see the genome of the virus is the entire RNA of the corona virus
specifically that we’re talking about here the ORF 1 aging and the ORF 1b gene
for those of you who are molecular biology buffs there’s actually a overlap
in that gene right here that requires a frame shift on the ribosome to be able
to translate both of these and we’ll talk more about that in the coming
sessions and updates what this here represents is where these mutations in
the genome are occurring we see that there’s a lot of mutations occurring
down here in these small genes and not so much here this s gene right here it
codes for the S protein we can see that there are some mutations some of these
mutations may not be actually changing amino acids
however this s protein is the spike protein on the very outside of the cell
this is the protein that is going to be binding to the ACE 2 protein on the
human lung cells that allows it to bind and infect them abstence ibly this is
the portion of the RNA genome of the virus that they would be injecting into
your cells as a possible vaccine so that your cells could take this instruction
make the S protein inside your body which would cause a antibody response
which would then give you the vaccine against the corona virus at this point
I’d like to talk to healthcare providers and people who are leaders in their
community people who are members of medical groups this is the time now to
start communicating with your patients educate them what are they supposed to
do if they get sick if they develop a fever if they develop a sore throat if
they are otherwise healthy they don’t have shortness of breath they’re not
hypotensive the best thing to do is to self quarantine and stay home do not
overburden your health care delivery system they’re going to be plenty busy
with people who are worse off if you are going to go to the hospital make sure
you call ahead find out what the procedures are because they’re going to
want to make sure that you’re isolated they’re gonna probably give you a mask
things to think about as well as make a plan on where to go
there are hotlines people are going to be calling in if you have a nurse advice
line make sure you double it or Triplette because the volume of calls
are going to increase people are going to be very concerned if you have the
ability to do telemedicine that’s what you should do
the corona virus cannot infect somebody over the phone next thing we need to do
is plan for a surge so that means that people who are in the hospital may be
overwhelmed and they may need to get into resources that are normally in the
outpatient setting people who are doing for instance well checks hospitals
themselves need to start thinking about hospitals within hospitals
so in other words a dedicated unit for people that you suspect as having
coronavirus a place that you would need to have negative pressure rooms so that
you’re not blowing out the aerosolize coronavirus into other parts of the
hospital something as practical as understanding that most operating rooms
are under positive pressure some of the more modern ones can switch to negative
pressure but if you take a coronavirus patient into a positive pressure
operating room that’s not going to be a good thing it could also be very
expensive to have the ability to have coronavirus treatment all throughout the
hospital you need to have a dedicated place where contact is minimized and the
people working in that area are going to have maximal PPE or personal protective
equipment and not have to burn through a lot of these materials because they’re
going to be limited so the time is now to start putting these procedures in
place now of course this situation is very fluid right now thanks for joining
us you

100 Comments

  • Reply MedCram - Medical Lectures Explained CLEARLY March 3, 2020 at 7:32 pm

    Please subscribe to get a notification when we release a new video.
    Visit us at https://www.MedCram.com for CME/CE and clear explanations of pneumonia, abdominal pain, sleep apnea, and over 60 other topics.
    All links referenced in this video are in the video description.
    Quick links to our other videos on Coronavirus (COVID-19):
    – Coronavirus Epidemic Update 28: Practical Prevention Strategies, Patient Age vs. Case Fatality Rate: https://youtu.be/quDYb_x54DM
    – Coronavirus Epidemic Update 27: Testing accuracy for COVID-19 (CT Scan vs. RT-PCR), California Cases: https://youtu.be/xQwfuJgJ9lo
    – Coronavirus Epidemic Update 26: Treatment Updates, Stock Markets, Germany & San Francisco, Pandemic? https://youtu.be/bV1CZxJ-uvU
    – Coronavirus Epidemic Update 25: Vaccine Developments, Italy's Response, and Mortality Rate Trends: https://youtu.be/UImSVhLLeGY
    – Coronavirus Epidemic Update 24: Infections in Italy, Transmissibility, COVID-19 Symptoms: https://youtu.be/wFoj2L2LpNA
    – Coronavirus Epidemic Update 23: Infections in Kids & Pregnancy, South Korea, Spillover From Bats: https://youtu.be/JGhwAGiAnJo
    – Coronavirus Epidemic Update 22: Spread Without Symptoms, Cruise Quarantine, Asymptomatic Testing: https://youtu.be/OqpHvK0XADY
    – Coronavirus Epidemic Update 21: Antibodies, Case Fatality, Clinical Recommendations, 2nd Infections?: https://youtu.be/9BYaywITXYk
    – Coronavirus Epidemic Update 20: Misinformation Spread, Infection Severity, Cruise Ship, Origins: https://youtu.be/Ka48UZDDzLY
    – Coronavirus Epidemic Update 19: Treatment and Medication Clinical Trials: https://youtu.be/4HK9QEy1KJ8
    – Coronavirus Epidemic Update 18: Cellphone Tracking, Increase in Hospitalizations, More Sleep Tips: https://youtu.be/vE4pBkslqS4
    – Coronavirus Epidemic Update 17: Spike in Confirmed Cases, Fighting Infections with Sleep (COVID-19): https://youtu.be/wlbM6VVkVZM
    – Coronavirus Epidemic Update 16: Strengthening Your Immune Response to Viral Infections (COVID-19): https://youtu.be/qqZYEgREuZ8
    – Coronavirus Epidemic Update 15: Underreporting, Prevention, 24 Day Incubation? (COVID19): https://youtu.be/o804wu5h_ms
    – Coronavirus Epidemic Update 14: Hospital spread of infection, WHO allowed in China, N-95 masks: https://youtu.be/pDnmHu8x9C4
    – Coronavirus Epidemic Update 13: Li Wenliang, nCoV vs Influenza, Dip in Daily Cases, Spread to Canada: https://youtu.be/0UgrPgJdzp0
    – Coronavirus Epidemic Update 12: Unsupported Theories, Pneumonia, ACE2 & nCoV: https://youtu.be/GT3_A1bf9pU
    – Coronavirus Epidemic Update 11: Antiviral Drugs, Treatment Trials for nCoV (Remdesivir, Chloroquine): https://youtu.be/pfGpdFNHoqQ
    – Coronavirus Epidemic Update 10: New Studies, Transmission, Spread from Wuhan, Prevention (2019-nCoV): https://youtu.be/gPwfiQgGsFo
    – Coronavirus Epidemic Update 9: Fecal-Oral Transmission, Recovery vs Death Rate: https://youtu.be/8Hjy3UfaTSc
    – Coronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine, & MRSA: https://youtu.be/GpbUoLvpdCo
    – Coronavirus Epidemic Update 7: Global Health Emergency Declared, Viral Shedding: https://youtu.be/nW3xqcGidpQ
    – Coronavirus Outbreak Update 6: Asymptomatic Transmission & Incubation Period: https://youtu.be/UGxgNebx1pg
    – Coronavirus Update 5: Mortality Rate vs SARS / Influenza: https://youtu.be/MN9-UXsvPBY
    – How Coronavirus Kills: Acute Respiratory Distress Syndrome (ARDS) & Treatment: https://youtu.be/okg7uq_HrhQ
    – Coronavirus Update 3: Spread, Quarantine, Projections, & Vaccine: https://youtu.be/SJBYwUtB83o
    – Coronavirus Symptoms, Diagnosis, Treatment: https://youtu.be/UCG3xqtcL3c
    – Coronavirus Outbreak – Transmission & Updates: https://youtu.be/9vMXSkKLg2I

  • Reply CartersCichlids March 3, 2020 at 9:51 pm

    Our family just stocked up on food and water and I recommend you do too just in case this gets out of control and we a quarantined I live in Indianapolis, Indiana btw.

  • Reply Authentic Shift March 3, 2020 at 9:51 pm

    That vaccine could go seriously wrong! Autoimmunity – I don't understand that you are so uncritically enthusiastic about it.

  • Reply HeHe HaHa March 3, 2020 at 9:51 pm

    You should take over who director job

  • Reply O.Alden Productions. March 3, 2020 at 9:52 pm

    I’m concerned about insurance and what happens if you don’t have insurance and you have severe symptoms?!

  • Reply Ai Vel March 3, 2020 at 9:52 pm

    My concern is with the USA's death numbers in comparison to the confirmed Conavirus COVID 19 patients. We are at almost a 7% death rate in the USA. We are supposed to be the medical leader of the world and the most prepared. How is it that our confirmed death rate is so high. Can you imagine everyone that is confirmed with this has a 7% chance of dying in the USA? Yesterday it was 75 confirmed and 6 dead in Washington state alone. They are saying on our new media children are not affected, but we see in Italy, Iran and other places around the world children are being infected. What types of medication should we be taking at home? We know this virus is not like the others because it is more aggressive. What Aggressive OTC meds do we need to take if we get infected?

  • Reply Rufus Kohn March 3, 2020 at 9:52 pm

    Is there any update on why and what percentage get re-infected?

  • Reply Kimberly Hudson March 3, 2020 at 9:55 pm

    Dr Schuchat told Senators today that CDC has substantially opened up the guidelines, but I don't know what she means by that? Does anyone know? It looks like it is still the same 3 categories: hospitalized with critical resp infection of unknown etiology, or hospitalized with serious respiratory infection of unknown etiology plus travel history, or close contact with known infected patients. ??

  • Reply Linda G March 3, 2020 at 9:56 pm

    Thanks for your informative videos. I like that you give the information: the good and bad, without going off on politically motivated rants as one other YouTube channel does. Your videos are very helpful.

  • Reply Cody March 3, 2020 at 9:56 pm

    It is going to get spicy

  • Reply Youneeda Lotsalove March 3, 2020 at 9:57 pm

    It was widely reported that the majority of Americans can't afford a $ 400 emergency. Hello Virus !!

  • Reply roman szefler March 3, 2020 at 9:57 pm

    One thing is to understand VIRUSES don't kill, weak immune system does. Seek how to be strong Sleep Don't Stress Enjoy outdoors and life

  • Reply David Johnson March 3, 2020 at 9:57 pm

    US government has wasted more than 2 months and emergency room physicians still have no test kits. Center for Disease Cover-up botched the job and with test
    kits and FDA bureaucrats are not any help. In a spread of virus every day counts and delays make tracing cases all but impossible. President Trump mentioned 43
    millions face masks stock in entire country and this supposed to cover 325 million Americans. People who have symptoms of flu should wear masks to protect
    others and be quarantined in their residence. Many people have no paid sick leave and have no health insurance. Without testing there is no difference between
    symptoms of seasonal influenza and Covid-19. I don't know how hospitals protect their workers in these dangerous times. Washington has totally dropped the ball
    and State and local governments are trying to deal with this mess. Hopefully various labs will be able to provide test kits and facilitate quicker diagnostics.

  • Reply Leadguitarman1 March 3, 2020 at 9:58 pm

    Why DO THESE HOSPITALS NOT HAVE A SEPARATE AREA SET UP FOR FLU AND COVID SUSPECTED PEOPLE?
    Keep them away from infecting emergency rooms and offices.

    Or better yet, have a mobile testing team? Lessons the need for resources.

  • Reply Ernestina Appiah-Boateng March 3, 2020 at 9:59 pm

    Thank you, this is the most in-depth information that I have found.

  • Reply Nora G March 3, 2020 at 10:00 pm

    How about for vapors, folks who vape?

  • Reply wileycoyotegenius1 March 3, 2020 at 10:01 pm

    The USA is going to be devastated by the virus because too many people wont be able to afford the medical bill so they just wont go to hospital

  • Reply Jake Wheelie March 3, 2020 at 10:01 pm

    3:30 – Politics at the worst time are sickening. This has to change.

  • Reply Mike Brown March 3, 2020 at 10:02 pm

    Better prepare to meet God. We are in the last days of the church age when pestilence and plagues are on the upswing in preparation for the mark of the beast/antichrist kingdom after the rapture of the church. 1Thessalonians 4:13-18; Revelation 13; Romans 10; Acts 20:21

  • Reply Ms Marie March 3, 2020 at 10:02 pm

    Thank you for your time. Stay Healthy.

  • Reply Eelke Aptroot March 3, 2020 at 10:03 pm

    Sounds like a good plan!

  • Reply Terrell Carey March 3, 2020 at 10:03 pm

    How can the CDC and everyone recommend washing your hands for 30 seconds with soap/water to prevent corona when they are just going to pick up their dirty-ass-never-cleaned phones…10 to 30 seconds later.
    Ironically to read or watch things abt said virus…

  • Reply Erica Lynn March 3, 2020 at 10:04 pm

    New case in Massachusetts today I’m in Maine but I also took my kids out of school already I am staying ahead of this my son has an auto immune system problem so I cannot take any chances I’m scared for my family my parents and grandparents

  • Reply Thomas Livingstone March 3, 2020 at 10:04 pm

    Containment in Tenerife is a joke I hear

  • Reply My Name March 3, 2020 at 10:05 pm

    Was wondering how many new deaths from the normal flu in Washington State?

  • Reply ScienceGuy March 3, 2020 at 10:10 pm

    I cannot believe that with a virus as serious as this we are already dropping the ball and making mistakes (ie, no testing). It's inexcusable.

  • Reply Brittany March 3, 2020 at 10:11 pm

    wear a mask, none are available. you are stuck going to ER with no mask.

  • Reply Yve Eriksson March 3, 2020 at 10:11 pm

    I heard Romney on TV thanking Trump for delaying the virus! Is he stupid? Not testing does not mean you don' have any virus cases. MOOOOOROOOON.

  • Reply ScienceGuy March 3, 2020 at 10:11 pm

    Meanwhile in NYC, nobody covers their cough or their sneeze. I see it ALL THE TIME on the subway. I know this city is doomed if people can't even do something as simple as cover their cough. I went to a restaurant earlier this week (it was an open buffet type restaurant) and I saw one of the cooks coughing openly, wasn't even doing anything to cover his cough and nobody was sending him home of course. smh…

  • Reply Brandy March 3, 2020 at 10:12 pm

    I JUST RETURNED FROM MY DR.S APPT AT EVERGREEN HOSPITAL. YES THE VERY HOSPITAL WITH ALL THE COVID DEATHS IN KIRKLAND. MY DOCTOR WONT TALK ABOUT COVID. HE SAYS ITS ALL BS AND NOTHING TO WORRY ABOUT. YEA LUCKY ME. AND NO I CANT EASILY CHANGE DOCTORS UNFORTANLEY AS I AM PERMANETLY DISABLED.

  • Reply Klaas Kuyer March 3, 2020 at 10:13 pm

    23 sick people in the Netherlands

  • Reply Nturavrg Chick March 3, 2020 at 10:13 pm

    Thank you for your updates. As someone who is having a lot of anxiety over this, your updates make me feel a tad more in control.

  • Reply Alucard March 3, 2020 at 10:13 pm

    I live 6 miles away from Kirkland, WA we are effectively the epicenter of this disease here in the US.

  • Reply Yo wut March 3, 2020 at 10:14 pm

    You get reinfected multiple times. The 'recovered' cases are not recovered but at danger.

  • Reply Human Person March 3, 2020 at 10:15 pm

    100% federally funded "TeleHealth" and "Home Testing Kits including a Thermometer" along with return mail packaging must be provided to anyone who requests either or both.

  • Reply anlacombe March 3, 2020 at 10:15 pm

    people who took the government offer to fly to the US from the cruise ship in japan and then spent more time in quarantine in the US were given $4000 bills from the government

  • Reply zrvs March 3, 2020 at 10:15 pm

    Someone needs to lobby for these tests to be affordable. Currently in Hawaii, they range from $1000-$3000 based on information from Queens Hospital and Urgent Care. Am not sure if it is because it is not officially deemed an epidemic/pandemic.

  • Reply Scarlet March 3, 2020 at 10:16 pm

    SK is doing aggressive ANTIBODY TESTING, to verify exposure among all the cultists in Daegu. The issue is whether you consider that data consistent with PCR & analogous in general given the behavior of the cult itself (I won't get into this, but there are behaviors that caused spread amongst the cultists). There's also the question of whether exposure to a virus that doesn't make you sick (so that you produce antibodies but never show signs or symptoms & never receive confirmatory PCR testing) is actually a case of the illness. Long story short, I'd look at Japan's data & the Diamond princess cruise ship data for the exact numbers

  • Reply Jelle Vreven March 3, 2020 at 10:17 pm

    In my town Helmond Netherlands 1 case yesterday 3 today.

  • Reply Jeremy Mcilvaine March 3, 2020 at 10:18 pm

    Hey doc

    THANK YOU SO MUCH! God bless you!

    I don’t think anyone of us could express the gratitude you so much deserve!

  • Reply Analog Fox March 3, 2020 at 10:19 pm

    yo, people!
    do not wear masks! the virus attacks those who fear it!

  • Reply Gerald's Videos March 3, 2020 at 10:21 pm

    Thanks again.

  • Reply Ardent Dfender March 3, 2020 at 10:22 pm

    Well, at some point in the future there will be Congressional hearings about the entire U.S. The Coronavirus Response! This Pandemic is picking up speed like a run away freight train going down hill fast!

  • Reply melloxmello March 3, 2020 at 10:23 pm

    Khan academy vibes, I trust this

  • Reply big daddy March 3, 2020 at 10:26 pm

    I cant believe US is charging over 3k for these tests. That's outrageous

  • Reply Mike L March 3, 2020 at 10:27 pm

    This is spreading way too fast on Friday only 1 person in the state of Washington contracted it TODAY 9 confirmed dead!!!

  • Reply Matt March 3, 2020 at 10:27 pm

    DEAR DR SEHEULT, please explain HOW SERIOUS the next ISOLATION PHASE is in each COUNTRY as they surpass 1500 – 2500 cases. IT IS NOT not NOT the time to throw in the towel!!!! We must FOLLOW CHINA's lead on this. FULL COUNTRY ISOLATION. Or it WILL RAMP UP and teach us about COMPOUND MATHEMATICS!!!!!!

  • Reply Jan Orr March 3, 2020 at 10:28 pm

    Thanks for sharing your knowledge! The Nextstrain website is Amazing!!

  • Reply Video Surge March 3, 2020 at 10:28 pm

    Hi, I know and you know something that acts just like Coronavirus but might if the right one is used can will do the same to Coronavirus what Coronavirus does to us and it's the most deadly thing on planet earth yet harmless to us all "bacterophage" and "virophages".

  • Reply Yasiel Puig March 3, 2020 at 10:28 pm

    The weird thing is COVID 19 was my stage name in the 90's when I was a DJ'ing raves in LA. COVID 19 on the ones and twos. In the mix.

  • Reply Mark Kooper March 3, 2020 at 10:29 pm

    I am curious if you think this virus will be taken out of global circulation? How many people does it have infect before it joins the ranks of the common cold and flu which tend to mutate enough to stay alive every year?

  • Reply RAINS ACOMING March 3, 2020 at 10:29 pm

    Fear mongering doctors who are so knowledgeable yet cant figure out the common cold more less the flu, but now this guy is an expert on the coronavirus!

  • Reply Alejandre Calvez March 3, 2020 at 10:31 pm

    Hi! Glad to hear scientific update from a medical doctor yourself! I have been an avid user of vegei/fruit juices for 8 yrs now….. I have observed that papaya leaves is useful for keeping our lungs healthy maybe your guys can have a look the components of this it might be the answer of this ncov …..just saying this might help ALOT…God bless

  • Reply Derek Whittom March 3, 2020 at 10:32 pm

    WHO has declared that asymptomatic transmission does not seem to occur with SARS-CoV-2. Any thoughts?

  • Reply ki8k March 3, 2020 at 10:32 pm

    Please do not freak out and purchase all of the N95 masks. The masks are made for the people who are one the front pine fighting the disease. We don’t want our medical workers getting sick they are the people who can help you. The other lower quality masks are for those who are sick to prevent them from spreading the disease as much. You should buy the lower quality masks just in case you get sick but don’t buy out all of the higher quality masks because our medical professionals need them.

  • Reply M E March 3, 2020 at 10:32 pm

    Thank you so much for these updates! Please keep them coming!!! 🙏🙏🙏

  • Reply Harry Brannigan March 3, 2020 at 10:32 pm

    How can you test for the virus when similar viruses will produce the exact antibodies. It's sounds bollocks to me. There are several pathogens both viral and bacterial which will produce the same symptoms. And many people are being falsely diagnosed as having the illness when in fact they haven't.

  • Reply mark dilkes March 3, 2020 at 10:32 pm

    PANDEMIC if it looks like a duck, walks like a duck, sounds like a duck it is a: well at the WHO its an elephant not a duck

  • Reply Bilal March 3, 2020 at 10:33 pm

    Are we going to survive this?

  • Reply Micheal Williamson March 3, 2020 at 10:34 pm

    This is what the United States of America and the world gets for you so-called Geniuses f*** around with s*** you have no business f**** around with. In layman's terms , what makes you think your God? Now you went and f*** up the world …

  • Reply mark dilkes March 3, 2020 at 10:35 pm

    USA money over life

  • Reply TravelWell March 3, 2020 at 10:38 pm

    In the UK no one would be going to the hospital. They call 111 and then someone will test them at home or at their local GP surgery. They are then taken a specialist isolation unit. This is working well. But doesn't seem sustainable.
    As far as I know, we are not only testing people who've been to those specific countries.

  • Reply infinightsky March 3, 2020 at 10:39 pm

    I would like to mention that the covid 19 stats on the website you mention are from two sources and they’re both out of China. I wouldn’t believe them if they said water is wet

  • Reply DIY3DTECH.com March 3, 2020 at 10:42 pm

    I am confused at what value a diagnostics kit would provide as we are already seeing community spread. Its impractical to just keep quarantine people and we don't have an approved treatment. Speaking of which, how come no one is talking about Israel? From what I read, they are close to a vaccine based upon some work they have been doing on another strain of corona virus. That might be an interesting to either debunk or enlighten your viewers. Keep up the great work as you were missed the past few days!

  • Reply Tina Phillips March 3, 2020 at 10:44 pm

    Could it be possible children be asymptomatic carriers for the mutations? Just a thought. And thank you for everything you do!

  • Reply Massimiliano Gallieri March 3, 2020 at 10:45 pm

    Ciao from Italy!

  • Reply Ross Marks March 3, 2020 at 10:46 pm

    looks at hongcouver looks at washington looks at Hongcouver* glares at the betas in charge….

  • Reply Da Malakay March 3, 2020 at 10:49 pm

    Can you provide insights on this?

    World health officials said Tuesday the case fatality rate for COVID-19 is 3.4% globally, higher than previous estimates of about 2%.

    "Globally, about 3.4% of reported COVID-19 cases have died," WHO Director-General Tedros Adhanom Ghebreyesus said during a press briefing at the agency's headquarters in Geneva. In comparison, seasonal flu generally kills far fewer than 1% of those infected, he said.

  • Reply Shirley Munro March 3, 2020 at 10:50 pm

    Are you considering infecting blood type O volunteers to build up an infected blood donor pool who can donate antibodies as universal donors?

  • Reply The Organic & Natural Vegan March 3, 2020 at 10:53 pm

    I think the fear of the unknown is more damaging than the virus! We will all suffer from the effects on the economy by reductions of daily business, travel etc.

  • Reply Mello X March 3, 2020 at 10:53 pm

    Well white people, you cant shoot your way out of this one. lol

  • Reply Jo Ann Funseth March 3, 2020 at 10:53 pm

    Narrow testing guidelines still in place here. Surge in flu-like symptoms being treated as seasonal flu. This is a resort town with thousands of visitors coming in every week. Wouldn't surveillance in community be warranted? What's up with this?

  • Reply John Russell March 3, 2020 at 10:54 pm

    Does Ephedrine/Guaifenesin help with symptoms or would it complicate the disease?

  • Reply O.A. Bud and Michael Ham March 3, 2020 at 10:54 pm

    Thanks for tracking all of this for us Doc, is it time to stock food and water?

  • Reply Polarcupcheck March 3, 2020 at 10:57 pm

    We were getting alot of negatives in Florida, but now we have 3 positive for coronavirus. Most were testing positive for the flu.

  • Reply Noelyn Baquilar March 3, 2020 at 10:59 pm

    Literally every country around Denmark has been affected, besides a week ago when the news came😷

  • Reply Mrtokitone March 3, 2020 at 11:01 pm

    It’s 5g that is causing the symptoms they call corona virus 🦠 60mhz is flipping the oxygen molecules that our body can’t breath in

  • Reply Dave H March 3, 2020 at 11:02 pm

    fear porn. joke..

  • Reply Mawmaw Sue March 3, 2020 at 11:03 pm

    I've been in self quarantine now since the 10th of January 2020. I get groceries delivered to my front porch and my medicines delivered from CVS. I have direct deposit into my bank account and work at home when I choose to work. I don't do this because of any covid19 virus I'm a recluse and like it that way. I've spend years working outside my home and spent thousands making my home, my haven away from other stupid people. Nearest neighbor several miles. I'm stocked, locked, and loaded and I've seen the world and at this point of my life see no reason to interact with those I don't choose to. I sleep when I'm tired and I eat when I'm hungry and I do exactly as I please. "Insolation is merely a recluses vacation"

  • Reply 2wheelpiracy March 3, 2020 at 11:04 pm

    Its accelerated because the dumb ass people in the US not being aggressive and treating this bad. STOP TRAVELING TO INFECTED AREAS. And, self quarantine will not work. People are way too greedy, lack empathy for others and are just generally stupid for "self quarantine". IT WILL SPREAD.

  • Reply Bella Lee March 3, 2020 at 11:10 pm

    We don’t even have N95 for healthcare workers in Washington State medical centers now. A few of my coworkers have been tested positive now.

  • Reply Sad Abdou March 3, 2020 at 11:14 pm

    1 confirmed case in tunisia 2/3/2020

  • Reply flexman909 March 3, 2020 at 11:14 pm

    I feel this virus is wide spread in Southern California. I work at a post office and just today I counted 132 customers that walk in with a cough, runny nose, and a 12 that said they felt feverish.

  • Reply jaja sjsj March 3, 2020 at 11:14 pm

    How tf is there 2000 cases in italy h-how i just dont get it..i really dont get it…

  • Reply Trent Castanaveras March 3, 2020 at 11:16 pm

    I'm glad you're ok.

  • Reply G Fisher March 3, 2020 at 11:16 pm

    Love your videos! Thank you so much for the time you take to put out this information. I greatly appreciate it. I want to go to medical school now LOL!

  • Reply Vadim Bolshakov March 3, 2020 at 11:17 pm

    Guys, PANDEMIC is spelled differently…

  • Reply Rethink Science March 3, 2020 at 11:17 pm

    The American medical industry is killing people as they can’t afford to go to the doctors this virus will race through America due to this

  • Reply Racker March 3, 2020 at 11:21 pm

    Thanks for the update.

  • Reply Xerp Gaming March 3, 2020 at 11:24 pm

    There are 2 confirmed cases in indonesia

  • Reply Carl Ryan March 3, 2020 at 11:27 pm

    Not testing is keeping the number of cases down giving false hope.

  • Reply Q March 3, 2020 at 11:28 pm

    Stop reporting China. The Chinese Government doesn't even believe their own numbers…

  • Reply chakvetadze March 3, 2020 at 11:28 pm

    i am much more optimistic, at the bigest epicentre in China (Hubei province) are 67000 confirmed cases. that is 1.1 % of population. this is worst case scenario, becouse this satrted there and they were not prepeared. and this number is not going to rise much, there were only 200 cases today in china. second worst case in china is Guangdong with 13500 confirmed cases. that is 0.0118% of population. i am not MD but i am an economist 😀

  • Reply Mike Essink March 3, 2020 at 11:28 pm

    Does anyone know if there is a test to know if you have had the virus? And if you had it you are immune to it? Because if that’s the case it’s handy to know for medical personnel or people who work in public places. They can provide the best help as well then.

  • Reply wei chen March 3, 2020 at 11:29 pm

    All the travelers should be in quarantine. Because no where is 100% save

  • Reply Higgs Boson March 3, 2020 at 11:30 pm

    Why run and hide…it will get us all in the end anyway. Cheers!

  • Reply J Moore March 3, 2020 at 11:32 pm

    Tests sent to homes and hopefully everyone turns them in via porch or other ways they pick up. Take wasted tax money and use it that way. Just an idea.

  • Reply Amelia Kotte March 3, 2020 at 11:33 pm

    Is there any evidence to suggest whether the CRF depends on the particular virus strain? And similarly, is there any evidence to suggest whether the virus becomes more potent as it mutates?

  • Reply MockTubeLOL March 3, 2020 at 11:35 pm

    For those still comparing to the flu:
    You're right on one thing, yes it is comparably as transmissible as the flu.
    -Although genetically it is a Coronavirus and not an Influenza virus, the symptoms are comparable to Influenza.
    -In just 2 months, Coronavirus has infected 10x more people than SARS ever did in its entire run.
    -The very people comparing it to the flu and denying its threat are the same people who will continue on their normal day and infect others as this virus is confirmed asymptomatic spread (no symptoms, but virus transmissible).
    -As it is still early days and statistics are developing daily, it would appear the mortality rate is similar to the flu, although it is still at least double that currently (0.1% vs 0.2%). The Flu causes up to 61,000 deaths per year. This can potentially mean 122,000 Coronavirus deaths per year by rate comparison.
    -The real issue people are forgetting is the high complication rate of approx 16-20%. If 5,000 are infected, expect approx 1000 to require medical attention Most hospitals do not have 1000 beds in ICU. If 5 million infected, you now need up to 1 million beds. This can very quickly overload healthcare and cause economic impact as a result.
    -How many people do you personally know have had the flu? How many people do you know have had Covid-19?
    -Although the chances of dying are low, the risk of being infected is so high it is almost guaranteed to circulate in your area in the next few months. Containment is near impossible at this point in time.
    -Other complications to consider: Rate and efficiency of testing. You may be surprised to find out, only 35 cases had been tested in the USA. Doctors are unable to get their hands on test kits.
    Travel bans are proving useless because 15,000 students from China returned to Australia via 3rd party destinations bypassing banned countries. One of those students is already confirmed positive in Brisbane.

  • Reply Leysner guillaume March 3, 2020 at 11:37 pm

    Is the DUST comming from the RED PLANEET.

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