Articles, Blog

CBD for Anxiety, Mood Swings, and other Nervous System Ailments

December 22, 2019

Hi, everybody. I’m Ezra. And today I’m going to talk about using CBD,
Cannabidiol, for anxiety, mood swings and issues of the nervous system. So I’m gonna well, one, you can find me at Don’t forget to go there or my live Facebook
feed, Ezra Helps, Today, I want to talk about what anxiety is
a little bit, just briefly. I’ll talk about CBD and how it’s interacting
in the body and then I’ll go into dosing a little bit. And this one’s a challenge for me because
I also feel anxiety. I feel anxious having to give a lecture. But it’s really important as a practitioner
that I have compassion for my patients and so I’ve used CBD and I’ve helped my own anxiety
and I’ve been able to walk a lot of people through using CBD and other cannabinoids to
regulate and tone and help their anxiety. So first of all, what is it? What is anxiety? Why does it happen? It’s one of these experiences and ailment
in the body that has both psychological and pathological or physical ailments. You know we have as adults often as when anxiety
comes online. Often after when in our 30s, 40s, 50s. We have our jobs and our mortgage and kids
and stress so we can have fear. We can get physical anxiety, where we feel
it sort of coursing in our body. We can have psychological anxiety where we’re
just staying up all night worrying about things. So some issues like OCD are also associated
with anxiety. The big one and something I deal with a lot
in my practice with clients is medication induced anxiety. So there’s a lot of medications out there,
one of the primary classes of medications is benzodiazepines. So benzos, drugs like Valium, Xanax, are supposed
to help anxiety but these drugs can be biphasic which means that some people can start to
feel anxiety after they take them and it can be very difficult to get off the drug. So medication can induce anxiety. Also PTSD, so post traumatic stress syndrome
or disorder is a factor in anxiety. People feel fearful after traumatic events. And then social anxiety is a really common
one and this is usually common with youth. So teenagers just sort of getting into high
school, having to speak up in class and things like that. Social anxiety is very real and very common
and often medicated with traditional medications. So in the research I did, there’s a lot of
evidence that early trauma can play a role in anxiety. Meaning, if you had a traumatic home environment
or experienced some acute trauma, even brain trauma in your youth that this can exacerbate
anxiety later in life. And now, they’re finding that there’s evidence
that the ECS, the endocannabinoid system, the largest feedback system on the body is
affected by trauma. And so if you have a traumatic event, your
endocannabinoid tone can decrease, can be off. And since Anandamide, Anandamide is the natural
chemical that humans produced that is mimicked by THC, the chemical that’s found in cannabis,
if that Anandamide is affected early by a trauma, this Anandamide is a factor in learning
and emotions. So if our Anandamide tone is off, what happens
during a trauma is that we can learn that that same trigger and whether it’s a car accident
is a good example and that if you’re in a car accident as a kid, you learn through the
endocannabinoid system and associate emotions with that car accident. So every time you get in a car, you may have
some anxiety. Now, Anandamide is associated with learning
and emotion and THC is also associated with reduced memory, right? People when they get high, they forget things. There’s a lot of debate about, okay, does
it permanently affect memory? Well, the point is if you’re learning positive
things then Anandamide or THC may help enhance those things. If you’re experiencing or learning negative
things, then it can enhance that. So the science is still thin. There’s a lot of research to do in this but
it makes sense that trauma and therefore affecting the endocannabinoid system can go both ways. It can help or hinder. And also, it’s very easy to test this theory
out in terms of what THC does in the body because THC can increase anxiety in a lot
of people and decrease anxiety in a lot of people. This is called biphasic as well. So traditional medications for anxiety can
go both ways and so can THC. THC is a very powerful chemical, having a
direct effect on cells. So some people who feel anxiety relief using
THC may over time start to get more anxiety because it’s having such a strong effect on
cells. This is similar to conventional meds that
might be helping for a little while but if you’re not addressing the underlying issues
of the anxiety, after a while, your body is like, “I need something to help my own system.” This is where CBD comes in. CBDs are really fascinating molecule. CBD in the endocannabinoid system is called
2AG. So CBD from the cannabis or hemp or marijuana
plant is called Cannabidiol. It mimics 2AG. 2AG is this chemical we produce
that’s a regulator, a toning regulator in our system, in our cells. It’s primarily in the immune system. It’s also in the nervous system. What’s interesting about it is that it actually
interacts with both the CB1 and CB2 receptors. CB1 just means the cannabinoid receptors that
receive THC or receive Anandamide. CB2 are the cannabinoid receptors that receive
CBD or 2AG. And so if 2AG or thus Cannabidiol, CBD, interacts
with both of those receptors and then we get an overall toning of the endocannabinoid system. But it’s not a very powerful compound. You don’t feel it strongly in your system. Most people don’t. I’ll talk about that a little bit how to dose
in case you do have sensitivity to CBD. But CBD has been shown to attenuate or bring
down the intensity of cortisol. Cortisol is what wakes us up in the morning. That’s the stress chemical and a great way
of taking CBD is to take it night and then it goes into the system and tones over time
and in the mornings, your cortisol as it comes online is not so intense so you just wake
up. You don’t wake up in a panic thinking your
day. This is something that I used CBD, thinking
about a stressful day and owning my own business as a cannabis consultant. I was using CBD to really buffer that cortisol
and keep it low in the morning. It was really helpful for me. I took about 60 milligrams every night before
I went to bed. So another aspect of anxiety is its interaction
with GABA receptors. So we’re not quite sure but GABA seems to
be … These are very pronounced receptors in the brain. They interact with the endocannabinoid system
and GABA is connected to anxiety. So peak worry and anxious energy as well as
depression, so sedated. This is often what happens. You get anxious. You go through all of this energy usage and
then you can’t sustain that amount of energy and you crush down into a depression. So CBD has been shown and this is just primarily
in mouse models, animal models now so the human trials are new, are coming online. But CBD seems to take those sharp edges of
the anxiety as well as the low values of depression and regulates. So it seems to be interacting in that GABA
receptor area. But this also points to something really important
when we’re talking about using CBD which is a nontoxic plant based compound but it can
interact with some drugs that are also interacting with these systems. So a lot of people if they’re on SSRIs so
these are traditional antidepressants. Sometimes they use it for anti-anxiety and
SNRIs, these are drugs like Effexor. So SSRIs are drugs like Prozac. SNRIs are drugs like Effexor. And these drugs can have interaction with
CBD. So far I’ve had hundreds and hundreds of clients
using my CBD and I haven’t had anyone say that they’ve had any negative interaction. I think it requires much higher doses and
hundreds of milligrams. But I do believe in the model of the FDA which
says like, “Look, we have to really prove these things. We have to understand what these drugs are
doing before we can just allow them to go out in the world. The irony is that CBD comes from a naturally
growing plant and so a lot of people are going to be taking the CBD but that’s why I’m here. We try to educate people about how to use
it properly. So if we’re talking about dosing, thinking
about drug interaction is a really important thing. A lot of people say start with 20 milligrams
of CBD. You’ll feel relaxed. In the studies, if we’re looking at real scientific
evidence for the reduction of anxiety using CBD, we are seeing 600 milligrams as being
a dose that reduces anxiety. So I have many clients who have hypersensitivity
to medication or who have very severe anxiety and I would never start them off on 600 milligrams
and I wouldn’t even start them off on 20 milligrams. And it’s important to know that there’s something
called a nonlinear dose curve or a U-shaped dose curve. This means that a very low dose can have one
effect. As it gets higher in dosage, the effect can
be less strong actually. And then as you get even higher, you might
find a sweet spot where the dose is effective and then as it gets, the dose gets even higher,
then its effectiveness goes down to zero just like a really tiny dose. So you create this little U-shaped curve. And I’ve really seen this a lot. So a lot of people, if I have clients who
are hypersensitive to medication and have anxiety around things, I’ll start them off
on half milligram of CBD. I’ve seen people have a response to that,
have a strong response. So it’s important to remember that using cannabinoids
as well as acknowledging our anxiety is subjective. We have to understand that not everybody’s
going to respond the same way and that even thinking about taking certain drugs that might
help anxiety can make us anxious. I know that sounds counterintuitive but I
see it all the time and I have to empathize with that. I have to say to them, “Look, don’t go into
CBD fast and furious just because it’s available at every sort of vape store and you can find
it anywhere. It’s really important to work with somebody
who knows what they’re doing and to ease into it. Because of that dose curve, that nonlinear
dose curve, you don’t know what your sweet spot is. It might be just a half milligram per day. That’s why I also recommend a course of CBD. So this is like taking a course. And I guess I shouldn’t say recommend. Let me edit that. I can make a suggestion. If I recommend CBD then that’s like a doctor
recommending a drug. CBD has not been approved by the FDA so no
one can technically recommend it because we don’t know what it’s for, right? So I’m basing all of my information off of
my client reports, so anecdotal evidence. But I’ve had hundreds and hundreds of clients
as well as my own usage. So I suggest a course of CBD and this is like
taking a course of antibiotics where you take it for 30 days to really see how it’s going
to get deeper into your system and affect your nervous system. It goes in. It’s interacting with those CB2 and CB1 receptors
like 2AG. It’s hovering outside of the cell. It’s not having a direct effect. This is why it’s a very subtle and light compound
but over time it tones. It tones the system and allows the nervous
energy to go back to a baseline. So for example, if you take 20 milligrams,
often CBD will come in a capsule. If you take 20 milligrams of CBD, you might
miss your two, five, eight, 10 milligram dose that’s really spot on for you and you’re jumping
right to 20 milligrams and you may not get anything. So that’s why I like to keep CBD in a liquid
form so that you can really start a tiny dose, a micro dose. And I also like to keep THC and CBD separate. So there’s a lot of talk and if you go to
a medical marijuana dispensary, you will find a lot of one to one ratio products or products
that have an equal amount THC and CBD. There’s definitely evidence that the two working
together can be more beneficial for pain, can attenuate anxiety better. But THC can cause anxiety, right? So if you need a high dose of CBD but you
can’t tolerate a high dose of THC, you don’t want them going up at the same rate. You don’t want to take a one to one ratio,
tincture or product and get too much THC in your system. So I always suggest, keep your CBD, THC separate
and then you can mix and match. Some people will actually smoke marijuana
and add CBD to it, to buffer the effects of THC. Some people will take CBD throughout the day
to keep their nervous system energy balance and then they’ll use THC in the evening to
have their Friday night as it were. So I hope this helps give an overview of how
CBD is entering the nervous system and toning it and affecting it. You can always reach out to me for questions
on the Ezra Help Facebook feed here or ask questions. And you can go to, sign for
a consultation and I’ll help you through it and you can also buy my CBD there. So thanks for joining me and I’ll see you
next week. Take care.


  • Reply Beccanertia October 1, 2018 at 1:12 pm

    Excellent explanation! I'm surprised this video doesn't have more views, very well done! CBD has absolutely helped me with my mood and anxiety. I'm taking 10-30mg full spectrum CBD (.03 THC), 2-3 times a day, and I'm pretty sure I can take less and get the same effect… and save some money! This is an expensive experiment, but absolutely worth it. I'm very happy with the results. Thank you!

  • Reply elchulo13agt November 28, 2018 at 3:22 pm

    That’s why they make 20:1 or 18:1 I’m very sensitive to thc like you mentioned it makes my anxiety worse but I’ve been experimenting with cbd and thc for about 12months now and I realized that cbd alone wasn’t as effective for my panic disorder until I started microdosing thc with it … once I started using a 20:1 versus just hemp cbd I got really good results and ofcourse dosage was a challenge but I’m pretty well dialed in now …. I take about 15mg of cbd with approx 1mg of thc 3 times a day and it has worked wonders for my panic anxiety and racing mind

  • Reply Ipostle January 7, 2019 at 2:16 am


  • Reply Lat Love February 20, 2019 at 11:50 am

    This video is amazing⭐️
    You are amazing!

  • Reply Felicia Cole Bailey May 15, 2019 at 7:23 pm

    Can you walk me through mine? I just started using cbd vape.

  • Reply Jimena Rodríguez June 15, 2019 at 4:50 am

    Can I take it with lithium?

  • Reply c d e December 9, 2019 at 4:50 am

    I have the constant worry. Or I sleep a lot due to depression. But my ADHD keeps me up. I have a hard time concentrating due to my ADHD. And I have PTSD due to my dad holding me over a cliff when I was a kid. I hate having social anxiety. And talking I'm front of ppl. I pray to God this helps. Because I've been on so many meds. That just don't and have not helped.

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